| Professional Development League | - | 2024-05-09 20:00 | Wigan Athletic U21 | | Crewe Alexandra U21 | |
| Professional Development League | - | 2024-05-03 21:00 | Millwall U21 | 5-0 | Wigan Athletic U21 | 4-0 |
| Professional Development League | - | 2024-04-29 20:00 | Wigan Athletic U21 | 1-3 | Watford U21 | 0-2 |
| Professional Development League | - | 2024-04-23 20:00 | Ipswich Town U21 | 2-0 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2024-04-19 20:00 | Wigan Athletic U21 | 2-0 | Coventry City U21 | 2-0 |
| Professional Development League | - | 2024-04-15 20:00 | Wigan Athletic U21 | 1-2 | AFC Bournemouth U21 | 0-1 |
| Professional Development League | - | 2024-04-12 20:00 | Wigan Athletic U21 | 1-2 | Hull City U21 | 0-2 |
| Professional Development League | - | 2024-04-09 20:00 | Cardiff City U21 | 1-1 | Wigan Athletic U21 | 1-1 |
| Professional Development League | - | 2024-04-02 19:00 | Sheffield Wednesday U21 | 2-0 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2024-03-25 21:00 | Wigan Athletic U21 | 2-1 | Swansea City U21 | 0-1 |
| Professional Development League | - | 2024-03-19 21:00 | Fleetwood Town U21 | 4-1 | Wigan Athletic U21 | 2-1 |
| Professional Development League | - | 2024-03-11 21:00 | Wigan Athletic U21 | 0-4 | Sheffield Wednesday U21 | 0-1 |
| Professional Development League | - | 2024-03-07 23:00 | Barnsley U21 | 4-2 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2024-02-26 21:00 | Crewe Alexandra U21 | 3-3 | Wigan Athletic U21 | 1-1 |
| Professional Development League | - | 2024-02-06 21:00 | Coventry City U21 | 1-0 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2024-01-31 03:00 | Hull City U21 | 3-4 | Wigan Athletic U21 | 2-2 |
| Professional Development League | - | 2024-01-22 21:00 | Wigan Athletic U21 | 0-3 | Sheffield United U21 | 0-1 |
| Professional Development League | - | 2024-01-15 21:00 | Wigan Athletic U21 | 0-5 | Birmingham City U21 | 0-4 |
| Professional Development League | - | 2024-01-09 21:00 | Burnley U21 | 1-1 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2023-12-18 21:00 | Wigan Athletic U21 | 5-1 | Peterborough United U21 | 4-1 |
| Professional Development League | - | 2023-11-29 22:00 | Wigan Athletic U21 | 1-2 | Fleetwood Town U21 | 0-1 |
| Professional Development League | - | 2023-11-21 21:00 | Peterborough United U21 | 1-1 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2023-11-07 22:00 | Sheffield United U21 | 5-1 | Wigan Athletic U21 | 2-0 |
| Professional Development League | - | 2023-10-30 21:00 | Wigan Athletic U21 | 5-0 | Barnsley U21 | 4-0 |
| Professional Development League | - | 2023-09-25 20:00 | Wigan Athletic U21 | 0-1 | Burnley U21 | 0-1 |
| Professional Development League | - | 2023-09-15 21:00 | Birmingham City U21 | 1-3 | Wigan Athletic U21 | 1-2 |
| Professional Development League | - | 2023-09-12 21:00 | Wigan Athletic U21 | 3-0 | Colchester United U21 | 2-0 |
| Professional Development League | - | 2023-09-05 20:00 | Bristol City U21 | 2-1 | Wigan Athletic U21 | 2-1 |
| Professional Development League | - | 2023-08-21 21:00 | Charlton Athletic U21 | 2-2 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2023-08-16 19:00 | Wigan Athletic U21 | 2-3 | Queens Park Rangers U21 | 2-1 |
| Professional Development League | - | 2023-05-09 20:30 | Queens Park Rangers U21 | 1-5 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2023-04-28 19:00 | Wigan Athletic U21 | 2-3 | Millwall U21 | 2-1 |
| Professional Development League | - | 2023-04-25 20:00 | Bristol City U21 | 1-2 | Wigan Athletic U21 | 1-1 |
| Professional Development League | - | 2023-04-17 20:00 | Wigan Athletic U21 | 2-1 | Reading U21 | 1-1 |
| Professional Development League | - | 2023-04-03 21:00 | Charlton Athletic U21 | | Wigan Athletic U21 | |
| Professional Development League | - | 2023-03-20 21:00 | Wigan Athletic U21 | 5-1 | Hull City U21 | 3-0 |
| Professional Development League | - | 2023-03-07 21:30 | Peterborough United U21 | 2-1 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2023-03-01 21:00 | Wigan Athletic U21 | 1-2 | Crewe Alexandra U21 | 1-1 |
| Professional Development League | - | 2023-02-20 22:00 | Burnley U21 | 0-3 | Wigan Athletic U21 | 0-1 |
| Professional Development League | - | 2023-02-13 21:00 | Wigan Athletic U21 | 1-0 | Coventry City U21 | 0-0 |
| Professional Development League | - | 2023-01-31 22:00 | Barnsley U21 | 1-0 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2023-01-17 21:00 | Wigan Athletic U21 | 5-0 | Birmingham City U21 | 2-0 |
| Professional Development League | - | 2023-01-11 01:00 | Sheffield United U21 | 3-3 | Wigan Athletic U21 | 2-1 |
| Professional Development League | - | 2022-11-22 21:00 | Wigan Athletic U21 | 2-0 | Sheffield Wednesday U21 | 1-0 |
| Professional Development League | - | 2022-11-07 21:00 | Wigan Athletic U21 | 1-6 | Barnsley U21 | 1-3 |
| Professional Development League | - | 2022-11-01 21:00 | Coventry City U21 | 2-2 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2022-10-25 02:00 | Hull City U21 | 1-3 | Wigan Athletic U21 | 0-2 |
| Professional Development League | - | 2022-10-17 21:00 | Wigan Athletic U21 | 2-1 | Peterborough United U21 | 0-1 |
| Professional Development League | - | 2022-10-10 20:00 | Crewe Alexandra U21 | 0-0 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2022-10-03 20:00 | Wigan Athletic U21 | 0-2 | Burnley U21 | 0-0 |
| Professional Development League | - | 2022-09-26 19:00 | Sheffield Wednesday U21 | 0-2 | Wigan Athletic U21 | 0-1 |
| Professional Development League | - | 2022-09-21 20:00 | Wigan Athletic U21 | 0-2 | Sheffield United U21 | 0-1 |
| Professional Development League | - | 2022-09-12 21:00 | Birmingham City U21 | 1-4 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2022-09-05 19:00 | Wigan Athletic U21 | 1-2 | Cardiff City U21 | 1-1 |
| Professional Development League | - | 2022-08-29 19:00 | Swansea City U21 | 3-0 | Wigan Athletic U21 | 1-0 |
| Professional Development League | - | 2022-08-24 21:00 | Wigan Athletic U21 | 1-2 | Colchester United U21 | 0-2 |
| Professional Development League | - | 2022-08-16 20:00 | Ipswich Town U21 | 3-1 | Wigan Athletic U21 | 0-1 |
| Professional Development League | - | 2022-08-10 20:00 | Wigan Athletic U21 | 5-0 | Watford U21 | |
