| Professional Development League | - | 2024-05-14 21:00 | AFC Bournemouth U21 | | Crewe Alexandra U21 | |
| Professional Development League | - | 2024-05-09 20:00 | Wigan Athletic U21 | | Crewe Alexandra U21 | |
| Professional Development League | - | 2024-05-06 19:00 | Sheffield United U21 | 6-0 | Crewe Alexandra U21 | 2-0 |
| Professional Development League | - | 2024-04-29 20:00 | Crewe Alexandra U21 | | Charlton Athletic U21 | |
| Professional Development League | - | 2024-04-26 21:00 | Hull City U21 | 3-0 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2024-04-22 20:00 | Crewe Alexandra U21 | 1-4 | Fleetwood Town U21 | 1-2 |
| Professional Development League | - | 2024-04-19 21:00 | Crewe Alexandra U21 | 1-3 | Cardiff City U21 | 0-0 |
| Professional Development League | - | 2024-04-15 20:00 | Crewe Alexandra U21 | 1-1 | Ipswich Town U21 | 1-1 |
| Professional Development League | - | 2024-04-09 20:00 | Queens Park Rangers U21 | 7-0 | Crewe Alexandra U21 | 6-0 |
| Professional Development League | - | 2024-04-03 02:00 | Birmingham City U21 | 3-1 | Crewe Alexandra U21 | 1-1 |
| Professional Development League | - | 2024-03-29 21:00 | Burnley U21 | 1-3 | Crewe Alexandra U21 | 0-0 |
| Professional Development League | - | 2024-03-18 21:00 | Crewe Alexandra U21 | 2-4 | Burnley U21 | 2-0 |
| Professional Development League | - | 2024-03-11 22:00 | Peterborough United U21 | 3-4 | Crewe Alexandra U21 | 2-1 |
| Professional Development League | - | 2024-03-04 21:00 | Crewe Alexandra U21 | 0-2 | Sheffield Wednesday U21 | 0-0 |
| Professional Development League | - | 2024-02-26 21:00 | Crewe Alexandra U21 | 3-3 | Wigan Athletic U21 | 1-1 |
| Professional Development League | - | 2024-02-13 21:00 | Coventry City U21 | 2-0 | Crewe Alexandra U21 | 0-0 |
| Professional Development League | - | 2024-01-15 21:00 | Crewe Alexandra U21 | 2-5 | Sheffield United U21 | 0-2 |
| Professional Development League | - | 2023-12-22 20:00 | Barnsley U21 | 3-0 | Crewe Alexandra U21 | 0-0 |
| Professional Development League | - | 2023-12-18 21:00 | Crewe Alexandra U21 | 1-2 | Barnsley U21 | 0-0 |
| Professional Development League | - | 2023-11-27 21:00 | Crewe Alexandra U21 | 1-6 | Coventry City U21 | 0-2 |
| Professional Development League | - | 2023-11-06 21:00 | Crewe Alexandra U21 | 0-3 | Birmingham City U21 | 0-0 |
| Professional Development League | - | 2023-10-31 21:00 | Sheffield Wednesday U21 | 2-1 | Crewe Alexandra U21 | 0-1 |
| Professional Development League | - | 2023-10-23 20:00 | Crewe Alexandra U21 | 1-1 | Peterborough United U21 | 1-0 |
| Professional Development League | - | 2023-09-26 20:00 | Fleetwood Town U21 | 4-6 | Crewe Alexandra U21 | 2-1 |
| Professional Development League | - | 2023-09-18 20:00 | Crewe Alexandra U21 | 0-2 | Hull City U21 | 0-1 |
| Professional Development League | - | 2023-09-11 21:00 | Crewe Alexandra U21 | 0-1 | Watford U21 | 0-1 |
| Professional Development League | - | 2023-09-04 21:00 | Millwall U21 | 2-0 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2023-08-28 20:00 | Crewe Alexandra U21 | 4-0 | Colchester United U21 | 2-0 |
| Professional Development League | - | 2023-08-21 20:00 | Swansea City U21 | 4-1 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2023-08-14 20:00 | Crewe Alexandra U21 | 1-1 | Bristol City U21 | 0-0 |
| Professional Development League | - | 2023-05-09 20:00 | Cardiff City U21 | 4-2 | Crewe Alexandra U21 | 2-2 |
| Professional Development League | - | 2023-05-05 20:00 | Crewe Alexandra U21 | 0-1 | Peterborough United U21 | 0-0 |
| Professional Development League | - | 2023-05-01 20:00 | Crewe Alexandra U21 | 0-2 | Bristol City U21 | 0-1 |
| Professional Development League | - | 2023-04-25 21:00 | Millwall U21 | 5-0 | Crewe Alexandra U21 | 2-0 |
| Professional Development League | - | 2023-04-11 19:00 | Crewe Alexandra U21 | 2-2 | Charlton Athletic U21 | 1-1 |
| Professional Development League | - | 2023-04-06 20:00 | Coventry City U21 | 0-0 | Crewe Alexandra U21 | 0-0 |
| Professional Development League | - | 2023-04-04 21:00 | Reading U21 | 4-0 | Crewe Alexandra U21 | 2-0 |
| Professional Development League | - | 2023-03-27 19:00 | Crewe Alexandra U21 | 3-2 | Ipswich Town U21 | 1-2 |
| Professional Development League | - | 2023-03-24 03:00 | Birmingham City U21 | 3-0 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2023-03-14 03:00 | Colchester United U21 | 1-1 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2023-03-01 21:00 | Wigan Athletic U21 | 1-2 | Crewe Alexandra U21 | 1-1 |
| Professional Development League | - | 2023-02-20 21:00 | Crewe Alexandra U21 | 3-1 | Hull City U21 | 2-0 |
| Professional Development League | - | 2023-02-13 21:00 | Crewe Alexandra U21 | 0-3 | Sheffield United U21 | 0-0 |
| Professional Development League | - | 2023-02-07 21:00 | Watford U21 | 1-2 | Crewe Alexandra U21 | 0-1 |
| Professional Development League | - | 2023-01-27 20:00 | Sheffield Wednesday U21 | 3-2 | Crewe Alexandra U21 | 2-1 |
| Professional Development League | - | 2023-01-24 21:00 | Burnley U21 | 3-4 | Crewe Alexandra U21 | 2-2 |
| Professional Development League | - | 2022-12-05 21:00 | Crewe Alexandra U21 | 3-1 | Barnsley U21 | 0-1 |
| Professional Development League | - | 2022-11-25 22:00 | Sheffield United U21 | 3-0 | Crewe Alexandra U21 | 2-0 |
| Professional Development League | - | 2022-11-08 21:00 | Crewe Alexandra U21 | 0-2 | Sheffield Wednesday U21 | 0-2 |
| Professional Development League | - | 2022-10-31 21:00 | Crewe Alexandra U21 | 0-2 | Birmingham City U21 | 0-2 |
| Professional Development League | - | 2022-10-21 20:00 | Barnsley U21 | 1-2 | Crewe Alexandra U21 | 1-1 |
| Professional Development League | - | 2022-10-10 20:00 | Crewe Alexandra U21 | 0-0 | Wigan Athletic U21 | 0-0 |
| Professional Development League | - | 2022-10-04 02:00 | Hull City U21 | 3-6 | Crewe Alexandra U21 | 2-3 |
| Professional Development League | - | 2022-09-26 20:00 | Crewe Alexandra U21 | 0-0 | Burnley U21 | 0-0 |
| Professional Development League | - | 2022-09-16 21:00 | Peterborough United U21 | 3-0 | Crewe Alexandra U21 | 1-0 |
| Professional Development League | - | 2022-09-12 20:00 | Crewe Alexandra U21 | 0-2 | Coventry City U21 | 0-1 |
| Professional Development League | - | 2022-09-05 19:00 | Crewe Alexandra U21 | 1-1 | Queens Park Rangers U21 | 1-0 |
| Professional Development League | - | 2022-08-22 21:00 | Crewe Alexandra U21 | 2-2 | Swansea City U21 | 1-0 |
